
时振振,男,1989年2月生,中共党员,理学博士,讲师。2018年6月毕业于中国科学院烟台海岸带研究所海洋化学专业,现就职于潍坊科技学院化工与环境学院,主要研究方向为海洋小分子天然产物结构与功能。主持一项国家自然科学基金青年项目一项,山东省自然科学基金青年项目和面上项目各一项,参与多项国家重点研发、国家自然科学基金面上项目等。以第一作者和通讯作者发表SCI论文10余篇,授权专利5项。
主持课题:
国家自然科学基金青年项目1项,42206130,基于种间互作的藻栖木霉抗围小丛壳菌活性分子研究,2023/01-2025.12,30万,主持,在研。
山东省自然科学基金面上项目1项,ZR2025MS681,基于共培养和生物转化策略探究深海木霉对链格孢的抑制作用,2025/07-2028.06,10万,主持,在研。
山东省自然科学基金青年项目1项,ZR2020QD102,两株藻栖木霉抗农业植物病原真菌活性成分研究,2021/01-2023/12,15万,主持,结题。
发表论文:
[1] Zhen-Zhen Shi, Xiang-Hong Liu, et al. Antifungal and antimicroalgal trichothecene sesquiterpenes from the marine algicolous fungus Trichoderma brevicompactum A-DL-9-2[J]. Journal of Agricultural and Food Chemistry, 2020, 68: 15440-15448.
[2] Zhen-Zhen Shi, Feng-Ping Miao, et al. Sesteralterin and tricycloalterfurenes A-D: terpenes with rarely occurring frameworks from the marine alga-epiphytic fungus Alternaria alternata k21-1[J]. Journal of Natural Products, 2017, 80(9): 2524-2529.
[3] Zhen-Zhen Shi, Feng-Ping Miao, et al. Trichorenins A−C, algicidal tetracyclic metabolites from the marine-alga-epiphytic fungus Trichoderma virens Y13‑3[J]. Journal of Natural Products, 2018, 81: 1121-1124.
[4] Zhen-Zhen Shi, Sheng-Tao Fang, et al. Trichocarotins A-H and trichocadinin A, nine sesquiterpenes from the marine-alga-epiphytic fungus Trichoderma virens[J]. Bioorganic Chemistry, 2018, 81: 319-325.
[5] Zhihao Hou, Zhenzhen Shi, et al. Organobromine compounds in aquatic environments: Embryotoxicity linked to lipophilicity and molecular structure[J]. Journal of Hazardous Materials, 2025, 489: 137550. (共同一作)
[6] Zhen-Zhen Shi, Xiu-Li Yin, et al. Trichoderols B-G, six new lipids from the marine algicolous fungus Trichoderma sp. Z43[J]. Marine Drugs, 2023, 21, 453.
[7] Zhen-Zhen Shi, Xiu-Li Yin, et al. A new harziane diterpene, harziaketal A, and a new sterol, trichosterol A, from the marine-alga-epiphytic Trichoderma sp. Z43[J]. Chemistry & Biodiversity, 2023, 20: e202301099.
[8] Zhen-Zhen Shi, Feng-Ping Miao, et al. Sulfurated diketopiperazines from an algicolous isolate of Trichoderma virens[J]. Phytochemistry Letters, 2018, 27: 101-104.
[9] Zhen-Zhen Shi, Xiu-Li Yin, et al. Two new isomeric tricycloalternarenes from the marine alga-epiphytic fungus Alternaria alternata k23-3[J]. Magnetic Resonance in Chemistry, 2018, 56(3): 210-215.
[10] Zhen-Zhen Shi, Sheng-Tao Fang, et al. Two new tricycloalternarene esters from an alga-epiphytic isolate of Alternaria alternata[J]. Natural Products Research, 2018, 32(21): 2523-2528.
[11] Zhen-Zhen Shi, Xiang-Hong Liu, et al. Sesquiterpenoids and a steroid from the algicolous Trichoderma brevicompactum[J]. Fitoterapia, 2021, 153: 104983.
[12] Zhen-Zhen Shi, Feng-Ping Miao, et al. Trichobisabolins A-H, eight new bisabolane derivatives from the marinealga-epiphytic fungus Trichoderma asperellum Y6-2[J]. Fitoterapia, 2019, 134: 372-377.
[13] Chang-Peng Li, Zhen-Zhen Shi, et al. Lipids and terpenoids from the deep-sea fungus Trichoderma lixii R22 and their antagonism against two wheat pathogens[J]. Molecules, 2023, 68: 6220.(共同一作)
[14] Xin-Yue Ma, Yin-Ping Song, et al. Three sesquiterpenes from the marine-alga-epiphytic fungus Trichoderma hamatum Z36-7[J]. Phytochemistry Letters, 2021, 43: 98-102.(共同通讯)
发明专利:
1.一种杜松烷倍半萜类化合物及其制备和应用,专利号:ZL201810366591.2
2.一种倍半萜三醇类化合物及其制备和应用,专利号:ZL201810367641.9
3.一种倍半萜烯醇类化合物及其制备和应用,专利号:ZL201810367046.5
4.一种胡萝卜烷倍半萜类化合物及其制备和应用,专利号:ZL201810367063.9
5. 一种环氧倍半萜类化合物及其制备和应用,专利号:ZL201810367035.7